4-Ethylphenylboronic acid, CAS 63139-21-9, is an arylboronic acid used primarily as a coupling building block in organic synthesis. Its para-ethyl-substituted phenyl group can be introduced into target molecules through reactions such as Suzuki–Miyaura cross-coupling, subject to the reaction design and conditions. The compound has the molecular formula C8H11BO2 and a calculated molar mass of 149.98 g/mol. For sourcing, confirm identity, assay, packaging, documentation, and delivery terms against your project requirements rather than relying on the name or CAS number alone.
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This guide is intended for procurement teams, process chemists, research laboratories, and chemical distributors evaluating 4-Ethylphenylboronic acid. It covers the compound’s basic identity, typical synthetic role, selection considerations, and practical sourcing questions. It is not a substitute for a reaction-specific procedure, a safety data sheet, or supplier documentation. Buyers should use the current product specification and safety information applicable to the offered lot.
4-Ethylphenylboronic acid is an organoboron compound whose boronic acid group is attached to a phenyl ring. The ethyl substituent is positioned at the 4-position, also described as the para position, relative to the boronic acid-bearing carbon. This substitution pattern gives the molecule a defined aromatic building block for synthesis planning. The CAS Registry Number supplied for the product is 63139-21-9.
The molecular formula, C8H11BO2, and calculated molar mass, 149.98 g/mol, are useful for checking identity and planning theoretical quantities. For example, 1 mmol corresponds to approximately 149.98 mg of pure compound, while 10 mmol corresponds to approximately 1.4998 g. These are stoichiometric calculations, not a statement of commercial assay or usable yield. Adjust actual weighing for the lot’s stated assay, moisture, and handling losses when relevant.
Arylboronic acids are commonly used as coupling partners in palladium-catalyzed Suzuki–Miyaura reactions, which can form carbon–carbon bonds between an aryl group and a suitable electrophilic partner. In this context, 4-Ethylphenylboronic acid may serve as the source of a para-ethylphenyl group. The reaction outcome depends on factors such as the coupling partner, catalyst system, base, solvent, temperature, and substrate stability. A chemist should confirm compatibility through literature review or project-specific experimentation rather than assuming identical performance across substrates.
Consider this material when a target structure requires a para-ethyl-substituted aryl unit and the planned route can use an organoboron coupling partner. Potential settings include research-scale synthesis, medicinal or materials chemistry development, and preparation of intermediates for further evaluation. These are broad application contexts, not guarantees of suitability for a particular compound or regulated use. Confirm the target molecule, route constraints, and required quality grade before procurement.
The para-ethyl group is part of the structure being transferred; it is not a catalyst or a general-purpose reaction additive. If your target instead requires an unsubstituted phenyl group or a different substitution pattern, another arylboronic acid may be a closer match. Route design should also account for competing functional groups and the stability of both coupling partners. Where those factors are uncertain, a small-scale feasibility assessment can help avoid committing to an unsuitable material or quantity.
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For this product, “type” generally refers to the specific chemical identity and the commercial grade or quality specification offered by a supplier, rather than a different material form. Do not assume that two listings with similar names have identical assay, impurity profile, moisture level, packaging, or documentation. Request the exact product name, CAS number, and lot-specific specification for the material being quoted. If your process has a defined impurity limit or analytical method, communicate it before order confirmation.
| Item to verify | Why it matters | Buyer action |
|---|---|---|
| Identity and CAS number | Helps distinguish the requested compound from similarly named materials. | Confirm CAS 63139-21-9 and the product name on the offer and documentation. |
| Assay and test method | Provides context for quantity calculations and intended use. | Request the stated value, method, and lot-specific certificate where available. |
| Impurities and moisture | May affect sensitive reactions or downstream processing. | Share project limits and ask whether the supplier can report relevant parameters. |
| Packaging and handling | Influences receipt, storage, and material handling at your site. | Confirm pack size, container type, and applicable handling instructions. |
Start with the intended use, required quantity, and acceptance criteria. Specify whether the material is for exploratory research, process development, or another defined purpose, because these uses may require different documentation or quality controls. State any critical assay, impurity, or moisture requirements in writing. If no project-specific limits are established, ask the supplier to provide the available specification and discuss whether it is appropriate for your application.
Price comparisons are meaningful only when the quoted material, assay basis, pack size, documentation, and delivery terms are comparable. Request the minimum order quantity, available package options, quote validity, estimated lead time, shipping terms, and any fees that apply to your destination. Availability and lead time can vary by quantity, production or sourcing status, and export requirements, so confirm them for the specific order. Avoid treating an indicative quote or generic catalog listing as confirmation of stock or dispatch timing.
For quantity planning, use the molecular mass as a starting point and then account for the stated assay and expected process consumption. As a theoretical illustration, 1 mmol of pure 4-Ethylphenylboronic acid is approximately 149.98 mg, and 10 mmol is approximately 1.4998 g. These figures do not include excess reagent, sampling, transfer losses, or reaction optimization needs. Align the requested pack size with the actual experimental or production plan to reduce avoidable inventory.
A reliable sourcing discussion should make the product identity and commercial scope clear before purchase. Ask the supplier to confirm what quality documents are available for the offered lot and whether the packaging and shipment can meet your destination and handling requirements. For international orders, verify the consignee details, import requirements, shipping terms, and any documentation needed by your organization. Do not infer regulatory status, certifications, or analytical performance unless these are explicitly documented for the product.
At Maison Chemical, we support B2B buyers evaluating 4-Ethylphenylboronic acid by discussing product identity, requested quantity, specification needs, packaging, and destination before an order is finalized. Sharing your required CAS number, target quantity, intended application, and any quality limits helps us assess the inquiry more efficiently. Documentation and commercial terms should be confirmed for the specific offered product and lot. We encourage buyers to review the supplied specification and safety information with their technical and procurement teams.
4-Ethylphenylboronic acid CAS 63139-21-9 is a para-ethyl-substituted arylboronic acid with the formula C8H11BO2 and a calculated molar mass of 149.98 g/mol. It may be suitable as an aryl building block in coupling routes when the target structure and reaction conditions support its use. The most practical sourcing decision depends on verified identity, lot-specific quality information, quantity, packaging, and confirmed delivery terms. To request a quotation from Maison Chemical, provide your required amount, destination, specification requirements, and preferred documentation so we can review the appropriate supply options with you.
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